Bronchoscopic Lung Volume Reduction for Emphysema

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Bronchoscopic lung volume reduction for emphysema: where next?

E mphysema is an irreversible disease and although patients derive significant benefit from inhaled therapies [1] and pulmonary rehabilitation [2], many remain significantly disabled. The National Emphysema Treatment Trial of lung volume reduction clearly showed that in appropriately selected patients it is possible to improve lung function, exercise capacity, quality of life and survival [3, 4...

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Bronchoscopic lung volume reduction

Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of ,25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed en...

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Bronchoscopic Lung Volume Reduction

The application of lung volume reduction surgery in clinical practice is limited by high postoperative morbidity and stringent selection criteria. This has been the impetus for the development of bronchoscopic approaches to lung volume reduction. A range of different techniques such as endobronchial blockers, airway bypass, endobronchial valves, thermal vapor ablation, biological sealants, and ...

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Bronchoscopic lung volume reduction for pulmonary emphysema: preliminary experience with endobronchial occluder.

OBJECTIVE To describe the self-expanding endobronchial occluder, as utilized in bronchoscopic lung volume reduction, with a 36 month follow-up procedure. METHODS Twenty-three subjects with severe emphysema were recruited and underwent flexible bronchoscopic placement of self-expanding endobronchial occluders. Outcomes were assessed at 1 week, 1-month, 3-, 6-, 12-, 24-, and 36-month intervals....

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Bronchoscopic lung volume reduction is springing with potential for patients with homogenous emphysema.

However, perceptions from the NETT study influenced the design of subsequent randomised controlled trials with endobronchial valves [7, 8] . The inclusion and exclusion criteria were similar and the focus was on patients with heterogeneous emphysema. Furthermore, the same CT scoring method was employed. This system is based on visually estimating severity of emphysema in three zones (upper, mid...

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ژورنال

عنوان ژورنال: International Journal of Cell Science & Molecular Biology

سال: 2017

ISSN: 2572-1100

DOI: 10.19080/ijcsmb.2017.02.555588